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  "Package": "MetaEntropy",
  "Title": "Functional Shannon Entropy for Virome Mutational Analysis",
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  "Date": "2026-02-09",
  "Authors@R": "c( person(\"Leandro Roberto\", \"Jones\", email = \"lrj000@gmail.com\", role = c(\"aut\", \"cre\"), comment = c(ORCID = \"0000-0002-5877-4194\")),\nperson(\"Julieta Marina\", \"Manrique\", role = c(\"aut\"), comment = c(ORCID = \"0000-0001-8712-6666\")))",
  "Description": "Estimates Shannon entropy, per gene and per genomic\nposition, associated with non-synonymous mutation frequencies\nin viral populations, such as wastewater samples. The package\nuses codon translations for functional insights. Each amino\nacid can be treated as an individual state, resulting in a\n20-state entropy computation, or grouped into one of six\nphysicochemical classes, adding further functional context.\nProvides normalized values (0-1 scale) to facilitate the direct\ncomparison of different genomic positions or total functional\nentropy across multiple metagenomes. Designed to analyze\nmutational data using tabular 'Single Nucleotide Variant' (SNV)\nfrequency tables generated by variant callers (e.g., 'iVar' or\n'LoFreq'), operating independently of consensus sequence\nestimation and multiple sequence alignment.",
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    "Date": "2026-06-07 07:16:53 UTC",
    "User": "root"
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  "Author": "Leandro Roberto Jones [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-5877-4194>), Julieta Marina\nManrique [aut] (ORCID: <https://orcid.org/0000-0001-8712-6666>)",
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    "entropyProfile",
    "getEntropySignature",
    "showMutations"
  ],
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      "title": "CDS topology and length of Wuhan-Hu-1 reference strain",
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      "page": "as.data.frame.entropyProfile",
      "title": "Coerce 'entropyProfile' to a Data Frame",
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        "as.data.frame.entropyProfile"
      ]
    },
    {
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      "title": "Evaluates Entropy Hotspot",
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      ]
    },
    {
      "page": "entropyProfile",
      "title": "Create (empty) object of class \"entropyProfile\"",
      "topics": [
        "entropyProfile"
      ]
    },
    {
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      "title": "Infer Entropy Signature",
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    },
    {
      "page": "mn908947.3",
      "title": "CDS topology and length of Wuhan-Hu-1 reference strain",
      "topics": [
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    },
    {
      "page": "plot.entropyProfile",
      "title": "Plot entropy signatures",
      "topics": [
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      ]
    },
    {
      "page": "print.profileSummary",
      "title": "Print method for 'profileSummary' objects",
      "topics": [
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      ]
    },
    {
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      "title": "Print method for 'tidyMutations' objects",
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      ]
    },
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      "title": "Summarize mutations",
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    },
    {
      "page": "wWater",
      "title": "Data from first and third COVID-19 waves in Trelew <http://tools.wmflabs.org/geohack/geohack.php?language=es&pagename=Trelew&params=-43.253333333333_N_-65.309444444444_E_type:city>",
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