# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "MetaEntropy" in publications use:' type: software license: MIT title: 'MetaEntropy: Functional Shannon Entropy for Virome Mutational Analysis' version: '1.3' doi: 10.32614/CRAN.package.MetaEntropy abstract: Estimates Shannon entropy, per gene and per genomic position, associated with non-synonymous mutation frequencies in viral populations, such as wastewater samples. The package uses codon translations for functional insights. Each amino acid can be treated as an individual state, resulting in a 20-state entropy computation, or grouped into one of six physicochemical classes, adding further functional context. Provides normalized values (0-1 scale) to facilitate the direct comparison of different genomic positions or total functional entropy across multiple metagenomes. Designed to analyze mutational data using tabular 'Single Nucleotide Variant' (SNV) frequency tables generated by variant callers (e.g., 'iVar' or 'LoFreq'), operating independently of consensus sequence estimation and multiple sequence alignment. authors: - family-names: Jones given-names: Leandro Roberto email: lrj000@gmail.com orcid: https://orcid.org/0000-0002-5877-4194 - family-names: Manrique given-names: Julieta Marina orcid: https://orcid.org/0000-0001-8712-6666 repository: https://jones-lr.r-universe.dev commit: c5c462a7f44b45f74a8ce57b31062c84a1ec2dd1 date-released: '2026-02-09' contact: - family-names: Jones given-names: Leandro Roberto email: lrj000@gmail.com orcid: https://orcid.org/0000-0002-5877-4194